I've finished my reta experiment as a lean individual starting in category one and as someone who almost definitely shouldn't have needed it to begin with.
43 - 5'11
starting 76kg/167lbs -> 69.9kg / 154lbs in 25 days
My last dexa was Oct 24 74kg 10%
I've tried to include as much data as possible to support this anecdotal journey.
The TLDR is that I reached a weight that:
a) I wasn't planning on reaching
b) I said I'd never go this low again
c) without really trying
70kg was my weight when I had a photoshoot in 2021 (I documented that journey in this group as well), using clen, t3, yohimbine and ECA. I remember pushing myself to brink of exhaustion e.g being unable to jog/dash across a pedestrian crossing that was just about to go from green to red. (although that was less of a cut, more of a trim)
This time - I didn't reduce calories as much and I never increased steps past 10k because I simply didn't need to.
My monthly average was 1930 cals, 158g protein, 68g fat, 143g carbs. Steps weekly average was 86633 - I never aimed to do more than 10k but walk to the gym, supermarket etc
I cut Jan-April for a holiday, increased steps and went VLC in the final fortnight. Then went from 73kg to 76kg in May-July due to poor diet adherence, frequent takeaways etc.
Without external motivation I struggle, which was one reason to give reta a go.
I've never used any GLP-1 previously.
My first dose was 2mg on 2nd July and I had considerably less morning and afternoon hunger for the first 3 days, with appetite returning slightly in the evening
I am willing to chalk this up to a combination of placebo, the retatrutide and also fatigue with my meal prep company. On day 4 I was out of prepped meals and had a desire for less bland food without a craving for junk options.
I decided to take the second dose of 2.5mg on day 5 because I was feeling hungrier (but not as hungry as pre-reta) in the morning, I then continued to redose every 5 days and started to increase the dose as well. I used up the 20mg vial this weekend
This was partly due to:
a) "chasing the dragon" of that initial peak hunger suppression
b) the rate at which I was losing weight meant I'd be at or past my goal weight with half a vial leftover if I stuck to 2.5mg doses
The scale graph speaks for itself. I've never had a cut that was almost a straight line down with barely any fluctuations. I was waking up nearly every day lighter than the prev day. 3 days out of last 28 were up slightly but then back down the following and 19/25 were lower.
My withings scales say I'm holding 2kg less water weight, which is what I'd expect to drop if I went low carb.
So:
Mild hunger suppression. It was enough to not go to bed hungry or be tempted for late night snacks, takeaway orders etc.
Instant diet adherence and killed cravings: Ihe first two weeks of a diet are hardest for me, ignoring the cravings etc until the results on scale start to show. I went from two takeaways a week to zero and had zero thoughts about swapping rice for a donut IIFYM etc
I have a can of sugar-free monster every morning with breakfast and buy a few 2 litre bottle of pepsi max a week, or a few 500ml bottles occasionally. I had zero desire or thoughts about pepsi this whole time
Is there a metabolic advantage with reta?
Based on this experience in contrast with my other cuts I would say yes - However, I was clearly laser dialled in and super consistent. I wasn't just trying to cut, I was trying to evaluate its potential as much as possible. If my food didn't have the exact nutrition information I didn't eat it - there was only 2-3 meals on the road where I only had calorie info.
I could have gone to 1500-1600 calories but I don't think I needed to. The aforementioned meal fatigue meant I was being lazy and eating things like air fryer chicken strips/chicken thighs instead of chicken breast and rice.
I can't recall in much detail my previous cuts except the pre-holiday one, except to say I've done the 20k+ steps a day, the 1500 cals and below, only eating lean protein and salad etc. Normally my stopping point is 72-73kg - perhaps getting lower after going VLC.
It's also worth mentioning I fall into the "permacut" cycle and abort surplus phases prematurely. I probably have some body dysmorphia because in the side by side pictures I'm probably lean enough at 75kg to stay in the surplus
If 2kg was water weight, then I've lost approx 1kg per week with a moderate deficit and a regular amount of exercise
SIDE EFFECTS:
1. Waking up every 2 hours like clockwork to pee - this was super annoying and is the biggest incentive for me to not wholeheartedly endorse reta.
2. HR is up from 60 to 78, and HRV is consistently lower too
3. sunburnt skin feeling
Energy and strength wise I felt fine until this past weekend. Yesterday was first day where my LISS walking was tough and I only did 30 minutes instead of the target 60. This last week my strength regressed and on Saturday I felt flat/hard to get a pump in the gym.
This would normally be where I would have a refeed. I definitely considered it but will save it for later this week as I have a DEXA booked for Thursday
Would I use it again?
The instant adherence is a big plus. But booking a holiday or similar event is usually enough incentive to start adhereing. If I wanted/needed 100% and instant adherence/consistency then it's probably worth it.
I'm curious how a lower weekly dose would support a lean bulk, but not sure if I'm willing to buy more to test and risk more disrupted sleep