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What does L-Glutamine actually do?

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Posted

I have 2 animo acid tabs after workout which contains 300mg of L-Glutamine but not sure what it is for, My peers tell me it helps the muscles recover but i would like your opinion.

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Posted

Glutamine in many physiological processes, the most important functions are donating nitrogen to the synthesis of NEAA's, and donating carbon to to the krebs cycle (aerobic energy release), synthesising ammonia to balance pH, as a building block for neurotransmitter synthesis in the brain, and as a fuel for many cells of the immune and digestive systems. It also is a preferential fuel for intestinal bacteria.

More related to bodybuilding it can help slightly increase HGH levels, is a required structural amino acid for building muscle, can help increase the volume of muscle cells (which increases their stored energy potential and contractile strength), and increases the rate of muscle repair after damage.

Despite all the good stuff though it's important to remember that the body can synthesise it's own glutamine very easily, and due to the preferential uptake of L Glutamine by the intestinal cells, only about 30-40% of any you supplement with actually reaches the blood supply or muscles. If taken in a high enough dose however (5-10g minimum), this can still be enough to make a difference.

The most pronounced effect from supplementing with decent sized amounts of glutamine is improved digestion and intestinal health, normally in a very obvious way after two weeks or so. Specific effects on muscle gain are far less pronounced, primarily because the body (in times of good health) mostly makes the glutamine it needs for anabolic purposes in the very cells that need it, and at the same time uses glutamine obtained from diet more for non anabolic purposes such as production of ammonia.

shinobi_85, Graham-jack, You and 1 other like this

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Posted

Well that answers that..... What a great post....:thumb:

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Posted

gotta rep that one

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Posted

600mg won't do much(if anything) mate, get the powdered version and throw 10-15g in your pre/post shake and before bed.

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Posted

600mg won't do much(if anything) mate, get the powdered version and throw 10-15g in your pre/post shake and before bed.

Too little dosage and needs to be taken on an empty stomach for maximum effectiveness. So first thing in the morning would be best.

0.34g/kg bodyweight is a better dosage.

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Posted

Glutamine in many physiological processes, the most important functions are donating nitrogen to the synthesis of NEAA's, and donating carbon to to the krebs cycle (aerobic energy release), synthesising ammonia to balance pH, as a building block for neurotransmitter synthesis in the brain, and as a fuel for many cells of the immune and digestive systems. It also is a preferential fuel for intestinal bacteria.

More related to bodybuilding it can help slightly increase HGH levels, is a required structural amino acid for building muscle, can help increase the volume of muscle cells (which increases their stored energy potential and contractile strength), and increases the rate of muscle repair after damage.

Despite all the good stuff though it's important to remember that the body can synthesise it's own glutamine very easily, and due to the preferential uptake of L Glutamine by the intestinal cells, only about 30-40% of any you supplement with actually reaches the blood supply or muscles. If taken in a high enough dose however (5-10g minimum), this can still be enough to make a difference.

The most pronounced effect from supplementing with decent sized amounts of glutamine is improved digestion and intestinal health, normally in a very obvious way after two weeks or so. Specific effects on muscle gain are far less pronounced, primarily because the body (in times of good health) mostly makes the glutamine it needs for anabolic purposes in the very cells that need it, and at the same time uses glutamine obtained from diet more for non anabolic purposes such as production of ammonia.

Sound advice, just what the doctor ordered.

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Posted

Another great use is for those on very low-carb diets....... Glutamine, when taken in high doses postworkout, can used by the body for modest amounts of Glycogen synthesis, along with fatty acids of course. This enables a reduction in sugar and starch intake (potentially Ketosis if you so desire), but still a high volume and intensity of training - for a few days anyway, then it's time to carb up!

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Posted

seems like a waste really now. Ive had a bag of this for about a year now and never bother using it really, not that there would be a pointg in doing lol.,

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Posted

When I had terrible bloating and stomach problems glutamine sorted it out almost instantly

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Posted

Glutamine helped with my stomach issues other than that I would not buy it

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