CLA study - UK-Muscle Body Building Community

Stu · 04-05-2005, 11:35 AM

Quote:

01/04/2005 - Supplements of conguated linoleic acid (CLA) taken for two years helped overweight adults keep their body fat mass down, without having to restrict calories or change exercise habits, shows a study published today.

The findings, published in the Journal of Nutrition, come from the extension of a 12-month study on 157 adults. It found that a daily intake of 3.4g of Tonalin brand CLA, made by Cognis, produced an average 9 per cent reduction in body fat mass.
While the second year of study was not carried out in double-blind conditions, and therefore cannot provide such strong evidence of efficacy, it does reflect high compliance levels for the product and its long-term safety.

“The high compliance and low drop-out rates indicate that long-term CLA supplementation was well-tolerated by subjects,” write the authors.

After the initial 12 month trial, published last spring in the American Journal of Clinical Nutrition, 134 of the participants volunteered to continue for another 12 months. Ethical reasons stopped the researchers from continuing the double-blind procedure.

“All patients knew they were taking CLA which minimises our findings somewhat,” said study co-ordinator Dr Jean-Michel Gaullier from Scandinavian Clinical Research in Kjeller, Norway.

“However the placebo group from the first year of study, which started the CLA treatment during the second year, showed the same decrease in body fat mass as those taking CLA in the first year. This confirmed our results from the initial trial,” he told NutraIngredients.com.

He added: “Those who continued to take the CLA maintained the lower amount of body fat mass, without decreasing it further, but without regaining the fat.”

As a general rule, a population with this kind of age profile should gain around 1kg each year, explained Dr Gaullier.

The researcher says that a 9 per cent body fat decrease represents about 2 kg in weight for a person weighing around 80kg to begin with, or the kind of weight loss that can be seen with a long-term exercise programme.

People on certain diets can lose up to 10 kg in the best case scenario but the benefit of CLA is that it does not affect the basal metabolic rate, according to Dr Gaullier. Other weight loss products reduce metabolic rates and this leads to weight regain.

CLA supplementation also appeared to lower levels of leptin, a hormone associated with increased weight. Over the course of 24 months, leptin levels dropped 20-35 per cent as study subjects lost body fat.

The researchers say that risk of side effects from CLA is no greater than in those taking the placebo. (They can only be properly measured in the first year, during placebo control). Most of those reported were unrelated to the use of CLA, with the remaining 6 per cent described as ‘mild’ reactions, most frequently gastrointestinal in nature, and seen equally across both CLA and placebo groups.

“The side effects were mainly due to capsules or the amount of oil ingested everyday that can affect some people,” said Dr Gaullier.

The new results suggest that people with the highest body mass index (BMI) and body fat mass, especially women with a 25 to 30 BMI, lose the most body fat on CLA supplementation.

Further research is needed to find out if obese people benefit even more.

“The best market for CLA would be those who are overweight but not yet obese. There is no treatment for these people so CLA could be interesting for them,” Dr Gaullier noted.

CLA is thought to work by lowering the amount of fat normally stored after meals, helping the body to break down and efficiently use fat.

Changes during the past 30 years in how cattle are raised (moving to grain feed over grass), coupled with the trend toward low-fat dairy and reduced beef consumption, have drastically reduced the amount of CLA humans acquire through diet

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ChefX · 04-05-2005, 01:48 PM

read thwho did the study?
list the reference please so we can read the actual information as this is just conclusions and could be twisted (usually is)

as if you read it says they lost 2kg over 12 months at 3.4g a day usage thats massive cost for so little a loss.

**Pscarb** · 04-05-2005, 03:31 PM

i could of placed money on you commenting on this 1st Rob

i have just used CLA for the 1st time with any consistency i took 2 750mg capsules with each meal and i do feel that it certainly contributed to my all time best condition 10 days ago on stage.

i was told to use it by my coach who is Harold Marillier (IFBB Pro) who was told to use it when dieting by both Dorian and Kerry kayes so to be honest if these guys give me advice like that i aint gonna argue. and it does seem to work...

ChefX · 04-05-2005, 03:47 PM

I'm glad it worked for you Paul (serious),
but the lab I worked with spent over $100,000 testing it (multiple versions, multiple amounts, multiple people and multiple support diets) and placebo worked better 99% of the time. I can't endorse it, and I have yet to see any study (legit as in teh material not the conclusions) that shows it works, there are just too many other things that work way better and cheaper.
Maybe just maybe after everything else is used, if you add this in you might get 1 extra oz off.
BUT if you try it and it does work, great, keep at it.
IMO

**Pscarb** · 04-05-2005, 04:28 PM

thats a fair point mate as you know i tend to go with real time experiances over studies but i have to mention that i would only use CLA when dieting as when i diet everything is spot on and written down so i can see what works and what doesnt i could not be sure it would be of an advantage to a BB who does not control his diet/supps as much...

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04-05-2005, 01:48 PM	#2 (permalink)
ChefX Getting HUGE! Join Date: Jan 2005 Location: A Secret Laboratory outside of Washington DC Posts: 1,870	read thwho did the study? list the reference please so we can read the actual information as this is just conclusions and could be twisted (usually is) as if you read it says they lost 2kg over 12 months at 3.4g a day usage thats massive cost for so little a loss.

04-05-2005, 03:31 PM	#3 (permalink)
Pscarb UK-Muscle Moderator and NABBA Champion Join Date: Jan 2005 Posts: 11,134	i could of placed money on you commenting on this 1st Rob i have just used CLA for the 1st time with any consistency i took 2 750mg capsules with each meal and i do feel that it certainly contributed to my all time best condition 10 days ago on stage. i was told to use it by my coach who is Harold Marillier (IFBB Pro) who was told to use it when dieting by both Dorian and Kerry kayes so to be honest if these guys give me advice like that i aint gonna argue. and it does seem to work...

04-05-2005, 03:47 PM	#4 (permalink)
ChefX Getting HUGE! Join Date: Jan 2005 Location: A Secret Laboratory outside of Washington DC Posts: 1,870	I'm glad it worked for you Paul (serious), but the lab I worked with spent over $100,000 testing it (multiple versions, multiple amounts, multiple people and multiple support diets) and placebo worked better 99% of the time. I can't endorse it, and I have yet to see any study (legit as in teh material not the conclusions) that shows it works, there are just too many other things that work way better and cheaper. Maybe just maybe after everything else is used, if you add this in you might get 1 extra oz off. BUT if you try it and it does work, great, keep at it. IMO

04-05-2005, 04:28 PM	#5 (permalink)
Pscarb UK-Muscle Moderator and NABBA Champion Join Date: Jan 2005 Posts: 11,134	thats a fair point mate as you know i tend to go with real time experiances over studies but i have to mention that i would only use CLA when dieting as when i diet everything is spot on and written down so i can see what works and what doesnt i could not be sure it would be of an advantage to a BB who does not control his diet/supps as much...