An introduction to Pro-Hormones - UK-Muscle Body Building Community

Langers · 29-04-2004, 04:48 PM

Pro-Hormones can generally be thought of more as Steroids than supplements and are converted into their target anabolic hormones (steroids) in the body by enzymes and therefore carry the many of same characteristics as the hormone they convert to. However, there is limit to how much of these substances can be enzymatically convertion and as a result their effects are not as strong as an actual steroid.

The following are the most common Pro-Hormones on the UK market a the moment:

1-Test & 1-AD

1-testosterone (17beta-hydroxy-5alpha-androst-1-en-3-one) is a steroid that is known as a 'double bond isomer' of the steroid testosterone. 1-AD (1-androstenediol, 1-androstene-3beta, 17beta-diol) is an oral prohormone that is converted to 1-testosterone by the enzyme 17beta-hydroxysteroid dehydrogenase and has significant oral activity.

Being a 5alpha-reduced androgen (a dihydrotestosterone (DHT) derivative), 1-test does not aromatize to oestrogens, unlike testosterone. This means that the risk of gynecomastia is low, and that water retention side effects are vastly reduced compared to other prohormones.

It is due to 1-testosterone's double bond isomer structure that 1-test is resistant to liver breakdown and is termed as 'orally active'.

Stacking 1-test with other prohormones may also be of value. The most common stack is with the testosterone precursor 4-AD. This stack will allow for a little extra size due to the water retaining properties of testosterone, and also might help minimize any loss of libido from the use of 1-AD alone. The precursor of the anabolic steroid nandrolone, 19-Nordiol is also often stacked with 1-test for similar reasons.

Side effects from 1-testostorone products can include:

Gastric upset - this can be relieved by consuming 1-test with a meal
Irritation while urinating - this can be avoided by making sure plenty of fluids are consumed

Lowered libido - this can be partially avoided by stacking the 1-AD with a 4-AD product

Lethargy - this can be partially avoided by again using 4-AD. Caffeine may also help due to it being a stimulant

Skin rash - this happens to a very small percentage of users and usually during the hot weather months

Increased appetite - this is just a response to your body wanting to grow

Insomnia - This can be partially avoided by taking your last dose earlier in the day

Acne - this is an androgenic side effect. Wash well and use a cleanser like Plexion

Acceleration of male pattern baldness - in susceptible individuals this can be a concern. If this runs in your family be aware of this

4-androstenediol (4-AD, 4-Diol) is a prohormone that is naturally found in the body and converts to testosterone (via the 3beta-HSD enzyme). 4-AD is a particularly anabolic prohormone, resulting in over 300% more conversion to testosterone than andro.

4-AD itself cannot convert to oestrogen and DHT making it a very popular pro-hormone. However, some androgenic or oestrogenic side effects can occur as a result of the conversion of the target hormone testosterone to oestrogen and DHT. Yet it is due to these side effects that 4-AD is commonly stacked with other prohormones, to help reduce the low testosterone and estrogen side effects (including loss of libido and lethargy) that they can cause. The most common substances that are stacked with 4-AD are 1-test/1-AD and 19-Nordiol.

The most common delivery methods for 4-AD are in oral capsule form, sublingual (beneath the tongue) and transdermal; the latter probably being the most effective method.

19-Nordiol

19-norandrostenediol (19-diol, 19-Nordiol) is a prohormone which converts to the anabolic hormone 19-nortestosterone (nandrolone). Like 4-diol this is also a very anabolic substance, with almost 100% more conversion to nandrolone than the older dione version. This can lead to gains in strength and muscle and also increased recovery times. 19-diol is also very long-lasting in the body and as a result doses can be spread out over a longer period in the day.

19-Nordiol does not convert to oestrogens or DHT prior to conversion. As nandrolone is the target hormone there is only a 20% conversion to DHT afterwards. This means that androgenic side effects, including hair loss and prostate enlargement are much less.

The most common delivery methods for 4-AD are oral capsule form and transdermal (which is probably the most effective method).

For more information, including where to purchase prohormones, check out UK Supplements

miami797 · 29-04-2004, 04:53 PM

forget the prohormones...they're a waste of money...just buy the real stuff

and dont forget that if you take a 19-nor and take a drud test it just shows up as nandralone and you are f*cked for usins steroids....so you might as well have used them in the first place

Langers · 29-04-2004, 05:01 PM

Which Pro-hormones have u used mate?

miami797 · 29-04-2004, 05:10 PM

everything from the old ANDRO-6 to paradeca to just regular 19-nor's and a list of other that i cant remember right now.....probably about 10 different types though and NONE of them seemed to cause any type of change.... and i was lucky enough to not get the random test that year when i took it since my friend on the same prohormone failed his tests and lost his NCAA eligability....

glutamine, amino acids, zma, vitamins, and diet will do alot more for growth then a prohormone.........

philipebrown · 30-04-2004, 08:40 AM

yeah ive used 1AD and 4AD before and they made me really tired! Slight gain in strenght but no real gains.

Langers · 30-04-2004, 08:29 PM

Quote:

Originally Posted by miami797

everything from the old ANDRO-6 to paradeca to just regular 19-nor's and a list of other that i cant remember right now.....probably about 10 different types though and NONE of them seemed to cause any type of change.... and i was lucky enough to not get the random test that year when i took it since my friend on the same prohormone failed his tests and lost his NCAA eligability....

glutamine, amino acids, zma, vitamins, and diet will do alot more for growth then a prohormone.........

well Andro and 19Nordione arent exactly great products and they are not discussed in this article.

I have used 1-AD and 4-AD over the course of 5 weeks and gained about 10-12lbs muscle. I don't consider this a waste of money.

Langers · 30-04-2004, 08:29 PM

Quote:

Originally Posted by philipebrown

yeah ive used 1AD and 4AD before and they made me really tired! Slight gain in strenght but no real gains.

At what doses mate?

I used 600mg 1-AD and 300mg 4-AD.

Euronymous · 18-05-2004, 04:51 PM

Hey guys & gals, I am not an expert in this field or anything but I do have experience with 1-AD and some of the other Andro alternatives. I started taking 1-AD about 7 months ago. I would take it before and after my workouts in 100mg doses along with some other basic supplements such as vitamins and protein powders. 1-AD worked well in that it enabled me to workout longer with a bit more weight than I normally used and helped me overcome the plateau I was currently on. But as time went on I noticed that 1-AD would have a lesser effect the more often I took it almost as if my body was building up a resistance to it. Against advice from others I increased the dosage to 150mg before and after workouts but took it with only every other workout. I workout 6 times a week so this resulted in taking it 3 out of 7 days a week at 300mg per day. I have been using it for about 5 months now.

The other day after taking my pre-workout dose I noticed a few rashes on my chest and legs. I immediately thought it must be this new laundry detergent that I was using and simply changed my clothes and went to the gym. By the time I got to the gym I now had rashes over 30% of my body and I had trouble seeing clearly along with being light headed and feeling confused. At this point I was in pretty bad shape so I called my mother who is a doctor and asked her what I should do. She suggested that is could be an allergic reactions to something new. Unable to workout in my current condition I went home to follow her advice and get some sleep. Before going to sleep I rewashed all my clothes in a new detergent and took a shower. When I woke up I was surprised to see that the rashes had gotten worse and now covered almost 40% of my body despite that fact that I had showered and removed all clothing washed in the new detergent. With the rashes this bad I was unable to go out in public as I now looked like a freak. So I stayed home and worked out but didn't take any supplements for the purpose of speeding up my metabolism and hopefully getting rid of whatever was causing these rashes. To my amazement after a hard workout, good meal and a little nap the rashes were gone. I thought nothing of it and decided that I must have come in contact with something outside my house that I was allergic to. The next day I woke up took my regular dose of goodies including 150mg 1-AD and went to the gym. When I got to the gym and changed into my workout gear I noticed that the rashes were back. I was then that I went home and did some research on 1-AD and discovered that it was causing rashes in some of the people who had taken it. Especially people who live or workout in hot weather climates as I do. With this information in mind I stopped taking 1-AD and the rashes immediately went away(After about 24 hours from last dose). This was 2 weeks ago and to this day if I take 1-AD I instantly break out with rashes each time a little more severe depending on the dose. I have no idea why the drug worked well for as long as it did(About 4 and a half months) and then stopped so suddenly and produced rashes. But I can no longer take 1-AD or any other andro alternatives because when I do these rashes instantly come back and each time are a little more severe and take longer to go away.

That was my experience with 1-AD, Feel free to share your thoughts...

18-05-2004, 06:26 PM

Welcome to the board, and well done, you've just won the award for the most 'rashes' in a story! I fancy a bacon sandwich now...

Deltmaster · 19-05-2004, 09:55 PM

nice one

**hackskii** · 19-05-2004, 10:05 PM

I tried the andro and did not notice anything.
Outside of gear, creatine and protein were the only thing I have noticed anything on.

Langers · 21-05-2004, 02:38 PM

Quote:

Originally Posted by Euronymous

Hey guys & gals, I am not an expert in this field or anything but I do have experience with 1-AD and some of the other Andro alternatives. I started taking 1-AD about 7 months ago. I would take it before and after my workouts in 100mg doses along with some other basic supplements such as vitamins and protein powders. 1-AD worked well in that it enabled me to workout longer with a bit more weight than I normally used and helped me overcome the plateau I was currently on. But as time went on I noticed that 1-AD would have a lesser effect the more often I took it almost as if my body was building up a resistance to it. Against advice from others I increased the dosage to 150mg before and after workouts but took it with only every other workout. I workout 6 times a week so this resulted in taking it 3 out of 7 days a week at 300mg per day.

So basically you started of on a low dose and then moved onto rediculous dosing schedule. Im not suprised its not working tbh

Quote:

I have been using it for about 5 months now.

I hope your joking!!

Langers · 21-05-2004, 02:39 PM

Quote:

Originally Posted by hackskii

I tried the andro and did not notice anything.

That would be because andro is crap. Andro is not discussed in this article cos its crap. Crap I tell thee

Langers · 21-05-2004, 02:43 PM

Quote:

Originally Posted by Euronymous

I have no idea why the drug worked well for as long as it did(About 4 and a half months) and then stopped so suddenly and produced rashes. But I can no longer take 1-AD or any other andro alternatives because when I do these rashes instantly come back and each time are a little more severe and take longer to go away.

omg

Please tell me you had PCT supplements after all this. pleeeease!!!

Panthro · 21-05-2004, 02:53 PM

i must admit, i am no fan of pro-hormones. I used Pro-Anabol a long time ago, made by CNP and got banned. What was that langers mate? i cant remember, but i had a very bad time off it.. wont go into that further! lol

Euronymous, i am not supprised they didnt work, ditto exactly what langers says! you need to do some serious research before you use products like that! I almost spat water all over my monitor reading that!!!

29-04-2004, 04:48 PM	#1 (permalink)
Langers Gym Addict Join Date: Nov 2003 Posts: 196	An introduction to Pro-Hormones Pro-Hormones can generally be thought of more as Steroids than supplements and are converted into their target anabolic hormones (steroids) in the body by enzymes and therefore carry the many of same characteristics as the hormone they convert to. However, there is limit to how much of these substances can be enzymatically convertion and as a result their effects are not as strong as an actual steroid. The following are the most common Pro-Hormones on the UK market a the moment: 1-Test & 1-AD 1-testosterone (17beta-hydroxy-5alpha-androst-1-en-3-one) is a steroid that is known as a 'double bond isomer' of the steroid testosterone. 1-AD (1-androstenediol, 1-androstene-3beta, 17beta-diol) is an oral prohormone that is converted to 1-testosterone by the enzyme 17beta-hydroxysteroid dehydrogenase and has significant oral activity. Being a 5alpha-reduced androgen (a dihydrotestosterone (DHT) derivative), 1-test does not aromatize to oestrogens, unlike testosterone. This means that the risk of gynecomastia is low, and that water retention side effects are vastly reduced compared to other prohormones. It is due to 1-testosterone's double bond isomer structure that 1-test is resistant to liver breakdown and is termed as 'orally active'. Stacking 1-test with other prohormones may also be of value. The most common stack is with the testosterone precursor 4-AD. This stack will allow for a little extra size due to the water retaining properties of testosterone, and also might help minimize any loss of libido from the use of 1-AD alone. The precursor of the anabolic steroid nandrolone, 19-Nordiol is also often stacked with 1-test for similar reasons. Side effects from 1-testostorone products can include: Gastric upset - this can be relieved by consuming 1-test with a meal Irritation while urinating - this can be avoided by making sure plenty of fluids are consumed Lowered libido - this can be partially avoided by stacking the 1-AD with a 4-AD product Lethargy - this can be partially avoided by again using 4-AD. Caffeine may also help due to it being a stimulant Skin rash - this happens to a very small percentage of users and usually during the hot weather months Increased appetite - this is just a response to your body wanting to grow Insomnia - This can be partially avoided by taking your last dose earlier in the day Acne - this is an androgenic side effect. Wash well and use a cleanser like Plexion Acceleration of male pattern baldness - in susceptible individuals this can be a concern. If this runs in your family be aware of this 4-androstenediol (4-AD, 4-Diol) is a prohormone that is naturally found in the body and converts to testosterone (via the 3beta-HSD enzyme). 4-AD is a particularly anabolic prohormone, resulting in over 300% more conversion to testosterone than andro. 4-AD itself cannot convert to oestrogen and DHT making it a very popular pro-hormone. However, some androgenic or oestrogenic side effects can occur as a result of the conversion of the target hormone testosterone to oestrogen and DHT. Yet it is due to these side effects that 4-AD is commonly stacked with other prohormones, to help reduce the low testosterone and estrogen side effects (including loss of libido and lethargy) that they can cause. The most common substances that are stacked with 4-AD are 1-test/1-AD and 19-Nordiol. The most common delivery methods for 4-AD are in oral capsule form, sublingual (beneath the tongue) and transdermal; the latter probably being the most effective method. 19-Nordiol 19-norandrostenediol (19-diol, 19-Nordiol) is a prohormone which converts to the anabolic hormone 19-nortestosterone (nandrolone). Like 4-diol this is also a very anabolic substance, with almost 100% more conversion to nandrolone than the older dione version. This can lead to gains in strength and muscle and also increased recovery times. 19-diol is also very long-lasting in the body and as a result doses can be spread out over a longer period in the day. 19-Nordiol does not convert to oestrogens or DHT prior to conversion. As nandrolone is the target hormone there is only a 20% conversion to DHT afterwards. This means that androgenic side effects, including hair loss and prostate enlargement are much less. The most common delivery methods for 4-AD are oral capsule form and transdermal (which is probably the most effective method). For more information, including where to purchase prohormones, check out UK Supplements Last edited by Langers; 08-03-2006 at 02:13 PM.

29-04-2004, 04:53 PM	#2 (permalink)
miami797 Feeling Slutty Join Date: Feb 2004 Posts: 1,440	forget the prohormones...they're a waste of money...just buy the real stuff and dont forget that if you take a 19-nor and take a drud test it just shows up as nandralone and you are f*cked for usins steroids....so you might as well have used them in the first place __________________ one in the pink. two in the stink.

29-04-2004, 05:01 PM	#3 (permalink)
Langers Gym Addict Join Date: Nov 2003 Posts: 196	Which Pro-hormones have u used mate? __________________ suppshop.co.uk - MultiBuy deals available

29-04-2004, 05:10 PM	#4 (permalink)
miami797 Feeling Slutty Join Date: Feb 2004 Posts: 1,440	everything from the old ANDRO-6 to paradeca to just regular 19-nor's and a list of other that i cant remember right now.....probably about 10 different types though and NONE of them seemed to cause any type of change.... and i was lucky enough to not get the random test that year when i took it since my friend on the same prohormone failed his tests and lost his NCAA eligability.... glutamine, amino acids, zma, vitamins, and diet will do alot more for growth then a prohormone......... __________________ one in the pink. two in the stink.

30-04-2004, 08:40 AM	#5 (permalink)
philipebrown Looking Freaky Join Date: Nov 2003 Location: north east Posts: 924	yeah ive used 1AD and 4AD before and they made me really tired! Slight gain in strenght but no real gains. __________________ "no, no, side chest franco, not front chest!........ ....and if you don't have it, don't hit it!" Arnold...from the making of pumping iron.

18-05-2004, 04:51 PM	#8 (permalink)
Euronymous Newbie Trainer Join Date: May 2004 Posts: 1	My reaction to 1-AD... Hey guys & gals, I am not an expert in this field or anything but I do have experience with 1-AD and some of the other Andro alternatives. I started taking 1-AD about 7 months ago. I would take it before and after my workouts in 100mg doses along with some other basic supplements such as vitamins and protein powders. 1-AD worked well in that it enabled me to workout longer with a bit more weight than I normally used and helped me overcome the plateau I was currently on. But as time went on I noticed that 1-AD would have a lesser effect the more often I took it almost as if my body was building up a resistance to it. Against advice from others I increased the dosage to 150mg before and after workouts but took it with only every other workout. I workout 6 times a week so this resulted in taking it 3 out of 7 days a week at 300mg per day. I have been using it for about 5 months now. The other day after taking my pre-workout dose I noticed a few rashes on my chest and legs. I immediately thought it must be this new laundry detergent that I was using and simply changed my clothes and went to the gym. By the time I got to the gym I now had rashes over 30% of my body and I had trouble seeing clearly along with being light headed and feeling confused. At this point I was in pretty bad shape so I called my mother who is a doctor and asked her what I should do. She suggested that is could be an allergic reactions to something new. Unable to workout in my current condition I went home to follow her advice and get some sleep. Before going to sleep I rewashed all my clothes in a new detergent and took a shower. When I woke up I was surprised to see that the rashes had gotten worse and now covered almost 40% of my body despite that fact that I had showered and removed all clothing washed in the new detergent. With the rashes this bad I was unable to go out in public as I now looked like a freak. So I stayed home and worked out but didn't take any supplements for the purpose of speeding up my metabolism and hopefully getting rid of whatever was causing these rashes. To my amazement after a hard workout, good meal and a little nap the rashes were gone. I thought nothing of it and decided that I must have come in contact with something outside my house that I was allergic to. The next day I woke up took my regular dose of goodies including 150mg 1-AD and went to the gym. When I got to the gym and changed into my workout gear I noticed that the rashes were back. I was then that I went home and did some research on 1-AD and discovered that it was causing rashes in some of the people who had taken it. Especially people who live or workout in hot weather climates as I do. With this information in mind I stopped taking 1-AD and the rashes immediately went away(After about 24 hours from last dose). This was 2 weeks ago and to this day if I take 1-AD I instantly break out with rashes each time a little more severe depending on the dose. I have no idea why the drug worked well for as long as it did(About 4 and a half months) and then stopped so suddenly and produced rashes. But I can no longer take 1-AD or any other andro alternatives because when I do these rashes instantly come back and each time are a little more severe and take longer to go away. That was my experience with 1-AD, Feel free to share your thoughts...

18-05-2004, 06:26 PM	#9 (permalink)
Insanity Guest Posts: n/a	Welcome to the board, and well done, you've just won the award for the most 'rashes' in a story! I fancy a bacon sandwich now...

19-05-2004, 09:55 PM	#10 (permalink)
Deltmaster Newbie Trainer Join Date: May 2004 Location: out in the sticks Posts: 3	nice one

19-05-2004, 10:05 PM	#11 (permalink)
hackskii Super Moderator Join Date: Jul 2003 Location: Sunny Southern California U.S.A. Posts: 22,649	I tried the andro and did not notice anything. Outside of gear, creatine and protein were the only thing I have noticed anything on. __________________ "Life is not measured by the number of breaths we take, but by the moments that take our breath away." - George Carlin Scott To view links or images in signatures your post count must be 0 or greater. You currently have 0 posts.

21-05-2004, 02:53 PM	#15 (permalink)
Panthro Getting HUGE! Join Date: Jan 2004 Posts: 1,508	i must admit, i am no fan of pro-hormones. I used Pro-Anabol a long time ago, made by CNP and got banned. What was that langers mate? i cant remember, but i had a very bad time off it.. wont go into that further! lol Euronymous, i am not supprised they didnt work, ditto exactly what langers says! you need to do some serious research before you use products like that! I almost spat water all over my monitor reading that!!! __________________ "looking at picutres of half naked men dont get you strong. Lets get down to business and go to the gym" - Svend Karlson. 'Viking Power'