BRABUS

I think this is the right section,,,

Whats peoples views on the below??? Certainly seems food for thought as its not the first time ive read something praising its benefits, as ive read elsewhere at some point by some authoritative/knowledgeable person ( unless in reality a keyboard expert, hahaha, but other posts i recall were also informative ) stating its something we could always be on beneficially........

NOTE:This is copied and pasted from Basskilleronline, so credit goes to him and the author JM2C.


Metformin is NOT oral insulin. People confuse it as such, because in most countries oral insulin is called Diamicron and metformin is called Diaformin.
When your body releases insulin, over time, your insulin receptors get 'dull', less responsive. In advanced stages that becomes type II diabetes.
Metformin 'refreshes' those receptors, making them more sensitive to the insulin that your body releases.
It is a great product. Taken straight after a large meal, within the hour you will have EXTREMELY full muscles. Dosages are 500mg after a normal to large carb meal, 1,000mg after a big carb meal and 1,500mg after all you can eat at Pizza Hut. You can take it after as many meals in a day as you wish, as long as those are large carb meals.
I generally found that if I take less than 100g of carbs for every 500mg metformin, I go into hypo. And yes, you can eat fat meals, as metformin will indirectly prevent the fat being deposited.
The long acting glucophage is taken before bed as it helps the person release less insulin throughout the night, especially if they had a big dinner like most people do. But that doesn't apply to a healthy person. That might get a healthy person in hypo overnight.
I believe every human should be on metformin, as it helps keep your insulin receptors fresh and as such it will prevent type II diabetes.

Glucophage doesn't cause hypoglycemia!
1- Gluco shut down your endogenous slin levels (the more slin-sensitivity, the less slin required)
2- Gluco blocks carbs absorption at intestinal level
3- Gluco inhibits gluconeogenesis
4- Gluco enhance slin receptor sensitivity
5- Gluco allows the body to produce more slin receptors
- glucophage has an activity of about 2 hours in our body (in healthy subjects; with renal dysfunctions it can reach 5 hours);
- it inhibits vitamin B12 absorption;
- it decreases VLDL levels;

this means that gluco can't do a carbs muscle loading if used alone, there aren't enough carbs and slin in your body to do this (see 2 and 3); the best way to do this, is a load/download diet regimen, with gluco in carbs download days and slin in load days.
remember: gluco is an antihyperglicemic drug, it isn't a macronutrients partitioning agent (as slin does)

JM2C

I plan on using it soon. It's pretty much beneficial for everyone and cheap. I think the maximum recommended dose per day is 2500mg. Also, besides lowering LDL levels, it also lowers triglyceride levels too.

LittleChris

Seems good to me, don't expect miracles though.
What it offers on paper is enough to persuade me, and cheap enough.
Have been using 1500mg daily and (500mg x 3- MD capsules) and has certainly helped in keeping me a little leaner.

__________________
"Just remember one thing, God has a plan for each and every one of us. All you have to do... is keep the faith and accept your cause" Ronnie Coleman

mick_the_brick

Interesting info mate

LukeVTS

hmmmmm. Good read. may look into that and get some more info.

Catsup007

I was interested in metformin as well, and well in simple terms, does it help to keep you leaner and gain lean muscle mass substantially? Is it worth it??

Catsup007

What about metformin + glyburide? Does it have the same effect as metformin only medication?

Catsup007

bump

erekose

Consistency FAIL

erekose

It's a very minor effect ime - but on the other hand it's not exactly expensive. Personally I think it's crappy horrible stuff that makes me feel ghastly, but there's literally masses of people that tolerate it just fine - it's very widely used.

Catsup007

When you tried it how did you dosed it and what kind of results did you get from it? Were you running it alongside aas or just metformin by itself?

Chris4Pez

bump for read in the morning

erekose

I've tried it various ways, including the fairly standard 500mg x 3 daily with large meals. I've gone higher and lower. Both with and without AAS. It works slowly over time, and I think if it wasn't for the extreme cheapness of it then I'd never have bothered after the first time.

Btw - lots of people get a bad case of the squits for a week or two before adjusting. Fortunately I don't, but be warned just in case!

BRABUS

Quote:

Originally Posted by BRABUS I think this is the right section,,, You can take it after as many meals in a day as you wish, as long as those are large carb meals. I generally found that if I take less than 100g of carbs for every 500mg metformin, I go into hypo. .... Glucophage doesn't cause hypoglycemia! ...

Consistency FAIL


dON'T UNDERSTAND THE ABOVE....AND CAN I JUST POINT OUT IN THE BOXED QUOTE....WHEREVER ITS FROM....IT IS NOT ME THE BOLD TYPE REFERS TO.....

Catsup007

Just of curiosity mate, when are you planning on using glucophage? I really would love to get advice by someone that has in fact tried it.