Fish oils to Enter Weight Loss Category? - UK-Muscle Body Building Community

ChefX · 17-02-2005, 06:07 PM

Fish oils to Enter Weight Loss Category?

Reprinted with permission from www.NutraIngredients.com, January 25, 2005

Emerging research looks set to position fish oils as a new ingredient for weight loss foods and supplements, reports Dominique Patton.

There is already evidence to link consumption of seafood with reduced risk of weight gain but there has been little knowledge so far about how this effect is produced. New studies carried out by one of the top three omega-3 suppliers, Pronova Biocare, have identified a potential mechanism for the weight reduction effect of fish-derived omega-3 fatty acids in mice.

The company, which will patent the findings on its concentrated DHA/EPA combination, says that a human trial underway in the Czech Republic may confirm the animal results in the coming months. “No mechanisms have been suggested for this effect to my knowledge. This is very new,” Morten Bryhn, director of research and development for Pronova Biocare, told NutraIngredients.com.

Researchers from the company and colleagues at Charles University and the Academy of Sciences of the Czech Republic in Prague report on their results in the December issue of Lipids (vol 39, pp 1177-1185). They showed that a 60 percent omega-3 concentrate, containing 50 percent docosahexaenoic acid and 10 percent EPA (known as EPAX 1050 TG) increased oxidation of fat by activating genes that break down fat in the mitochondriae and peroxisomes.

The fish oil concentrates not only caused weight reduction in the mice but they also appeared to stop the animals from gaining weight when given free access to food. Additionally, the omega-3 concentrate reduced the number of fat cells, especially in the abdominal region. These effects were increased in animals that were put on a 10 percent calorie reduction regime.

The regimen was previously tested in a pilot study, presented at the North American Association for Study of Obesity (NAASO) meeting in November (abstract no 249-P). It involved 20 women with severe obesity (body mass index of more than 40) who were already on a very low calorie diet.

The group given the omega-3 concentrate reduced their weight by 20 percent more than the placebo group after only three weeks of treatment (7.55 kg compared to 6.07kg in the placebo group). BMI was reduced by as much as 15 percent, says Pronova.

The firm has now initiated a larger study of 30 obese women to confirm these findings. The trial, as well as the previous pilot trial, will also give researchers the chance to check the mechanism identified in mice by analyzing biopsies of fat tissue taken from the patients. “We are planning to present these results at Vitafoods in May,” Dr Bryn said. “Most products in this area make a lot of promises for fast weight loss. But this really targets the mechanism behind weight gain and offers the possibility for weight loss,” he added.

Being overweight is not only a problem of too much food and too little exercise but also a problem of bombarding genes with signals leading to fat accumulation, explained Dr Bryn. “A diet rich in red meat and vegetable oils increases accumulation of fat in fat tissue because of a chronic disarray of genes responsible for handling fatty acids and carbohydrates.”

He explained that the number of fat cells increases, boosting the turnover of carbohydrates into fat. The resulting overweight or obesity is difficult to curb by calorie reduction and exercise only. “Genes are constantly programmed to a situation of starvation and they need to be reprogrammed. Omega-3 fatty acids from seafood seem to do exactly that,” added Dr Bryhn.

The findings support yet another benefit from omega-3 fatty acids, already being added to foods designed to improve heart health.

The weight loss category of foods and supplements is currently booming (worth more than $3 billion per year in the US) based on rising numbers of overweight people around the world. It is set to grow even faster in coming years as increasing numbers of children are already overweight.

Experts estimate that almost 25 percent of children in the EU are now obese, with about 400,000 becoming either obese or overweight every year. However Dr Bryhn claims that Pronova products will not “produce a dramatic effect, but should be marketed with a reasonable type of weight control diet".

Omega-3 fatty acids could be at an advantage over some other weight loss ingredients because of their long, safe history of therapeutic use. Some products have been patented for use in pharmaceuticals targeting specific health conditions or diseases and there are hundreds of clinical trials backing their safety.

(told ya! Chef x, see my alchemy!!!!)

ONE SMART COOKIE · 17-02-2005, 07:53 PM

Interesting read.

What about other types of fish oils like shark liver oil and squalene both of which could be beneficial to the heart and immune system and even cholesterol levels????

Do these come under the same wing as fish oils as above or could be used in a totally different way or are useless?????

Also during the manufacturing process how do they remove all the toxins from the fish oils which we are being told that are leaching into the seas and eco system in ever increasing amounts.

**hackskii** · 17-02-2005, 08:01 PM

Quote:

Originally Posted by ChefX

Fish oils to Enter Weight Loss Category?
Being overweight is not only a problem of too much food and too little exercise but also a problem of bombarding genes with signals leading to fat accumulation, explained Dr Bryn. “A diet rich in red meat and vegetable oils increases accumulation of fat in fat tissue because of a chronic disarray of genes responsible for handling fatty acids and carbohydrates.”

I thought this perticularly interesting.

Now is this from the vegetable oils or the red meat?

ChefX · 17-02-2005, 10:47 PM

first thos etoxins are in the liver of the fish, not the skns and flesh where they pull the oils from so the toxin levels ar almost none existant in other words the whole mecury scam was just that a scam.

ChefX · 17-02-2005, 10:48 PM

hackskii it was actually too little protein to fat/carb ratios and vegetable oils are non active only meat and fish oils (an oil form meat) are active

**hackskii** · 18-02-2005, 01:46 AM

Quote:

Originally Posted by ChefX

hackskii it was actually too little protein to fat/carb ratios and vegetable oils are non active only meat and fish oils (an oil form meat) are active

Glad you cleared that one up for me

For a second, I thought I was eating too many fish oils with my meat

17-02-2005, 06:07 PM	#1 (permalink)
ChefX Getting HUGE! Join Date: Jan 2005 Location: A Secret Laboratory outside of Washington DC Posts: 1,870	Fish oils to Enter Weight Loss Category? Fish oils to Enter Weight Loss Category? Reprinted with permission from www.NutraIngredients.com, January 25, 2005 Emerging research looks set to position fish oils as a new ingredient for weight loss foods and supplements, reports Dominique Patton. There is already evidence to link consumption of seafood with reduced risk of weight gain but there has been little knowledge so far about how this effect is produced. New studies carried out by one of the top three omega-3 suppliers, Pronova Biocare, have identified a potential mechanism for the weight reduction effect of fish-derived omega-3 fatty acids in mice. The company, which will patent the findings on its concentrated DHA/EPA combination, says that a human trial underway in the Czech Republic may confirm the animal results in the coming months. “No mechanisms have been suggested for this effect to my knowledge. This is very new,” Morten Bryhn, director of research and development for Pronova Biocare, told NutraIngredients.com. Researchers from the company and colleagues at Charles University and the Academy of Sciences of the Czech Republic in Prague report on their results in the December issue of Lipids (vol 39, pp 1177-1185). They showed that a 60 percent omega-3 concentrate, containing 50 percent docosahexaenoic acid and 10 percent EPA (known as EPAX 1050 TG) increased oxidation of fat by activating genes that break down fat in the mitochondriae and peroxisomes. The fish oil concentrates not only caused weight reduction in the mice but they also appeared to stop the animals from gaining weight when given free access to food. Additionally, the omega-3 concentrate reduced the number of fat cells, especially in the abdominal region. These effects were increased in animals that were put on a 10 percent calorie reduction regime. The regimen was previously tested in a pilot study, presented at the North American Association for Study of Obesity (NAASO) meeting in November (abstract no 249-P). It involved 20 women with severe obesity (body mass index of more than 40) who were already on a very low calorie diet. The group given the omega-3 concentrate reduced their weight by 20 percent more than the placebo group after only three weeks of treatment (7.55 kg compared to 6.07kg in the placebo group). BMI was reduced by as much as 15 percent, says Pronova. The firm has now initiated a larger study of 30 obese women to confirm these findings. The trial, as well as the previous pilot trial, will also give researchers the chance to check the mechanism identified in mice by analyzing biopsies of fat tissue taken from the patients. “We are planning to present these results at Vitafoods in May,” Dr Bryn said. “Most products in this area make a lot of promises for fast weight loss. But this really targets the mechanism behind weight gain and offers the possibility for weight loss,” he added. Being overweight is not only a problem of too much food and too little exercise but also a problem of bombarding genes with signals leading to fat accumulation, explained Dr Bryn. “A diet rich in red meat and vegetable oils increases accumulation of fat in fat tissue because of a chronic disarray of genes responsible for handling fatty acids and carbohydrates.” He explained that the number of fat cells increases, boosting the turnover of carbohydrates into fat. The resulting overweight or obesity is difficult to curb by calorie reduction and exercise only. “Genes are constantly programmed to a situation of starvation and they need to be reprogrammed. Omega-3 fatty acids from seafood seem to do exactly that,” added Dr Bryhn. The findings support yet another benefit from omega-3 fatty acids, already being added to foods designed to improve heart health. The weight loss category of foods and supplements is currently booming (worth more than $3 billion per year in the US) based on rising numbers of overweight people around the world. It is set to grow even faster in coming years as increasing numbers of children are already overweight. Experts estimate that almost 25 percent of children in the EU are now obese, with about 400,000 becoming either obese or overweight every year. However Dr Bryhn claims that Pronova products will not “produce a dramatic effect, but should be marketed with a reasonable type of weight control diet". Omega-3 fatty acids could be at an advantage over some other weight loss ingredients because of their long, safe history of therapeutic use. Some products have been patented for use in pharmaceuticals targeting specific health conditions or diseases and there are hundreds of clinical trials backing their safety. (told ya! Chef x, see my alchemy!!!!) __________________ *To view links or images in signatures your post count must be 0 or greater. You currently have 0 posts.* *The Regimen X Bodybuilding System by The Family of X* In the great Greek poem by Constantine Cavafy titled "Ithaka," We are reminded that it is the voyage and the adventures on the way that count, not the arrival itself.

17-02-2005, 10:47 PM	#4 (permalink)
ChefX Getting HUGE! Join Date: Jan 2005 Location: A Secret Laboratory outside of Washington DC Posts: 1,870	first thos etoxins are in the liver of the fish, not the skns and flesh where they pull the oils from so the toxin levels ar almost none existant in other words the whole mecury scam was just that a scam. __________________ *To view links or images in signatures your post count must be 0 or greater. You currently have 0 posts.* *The Regimen X Bodybuilding System by The Family of X* In the great Greek poem by Constantine Cavafy titled "Ithaka," We are reminded that it is the voyage and the adventures on the way that count, not the arrival itself.

17-02-2005, 10:48 PM	#5 (permalink)
ChefX Getting HUGE! Join Date: Jan 2005 Location: A Secret Laboratory outside of Washington DC Posts: 1,870	hackskii it was actually too little protein to fat/carb ratios and vegetable oils are non active only meat and fish oils (an oil form meat) are active __________________ *To view links or images in signatures your post count must be 0 or greater. You currently have 0 posts.* *The Regimen X Bodybuilding System by The Family of X* In the great Greek poem by Constantine Cavafy titled "Ithaka," We are reminded that it is the voyage and the adventures on the way that count, not the arrival itself.

17-02-2005, 07:53 PM	#2 (permalink)
ONE SMART COOKIE Decided to leave due to idiots & and their over inflated egos Join Date: Jun 2004 Posts: 2,015	Interesting read. What about other types of fish oils like shark liver oil and squalene both of which could be beneficial to the heart and immune system and even cholesterol levels???? Do these come under the same wing as fish oils as above or could be used in a totally different way or are useless????? Also during the manufacturing process how do they remove all the toxins from the fish oils which we are being told that are leaching into the seas and eco system in ever increasing amounts.