Metformin

[The Animal]

What use dose Metformin (Glucophage) have whilst run alongside insulin?

What dose it do? And why?

I know what it is, my grandad is prescribed it because he's type two diabetic.

Has anyone ever used it?

Chers dudes.

[D-TROPIN]

I used it a while ago!

gave me the major sh**s as one of its main side effects!!!

i used 250mg(half a tablet of 500) with every meal so 1500mg per day!

worked v well and felt really full and pumped....unfortunately so did my toilet!!!!

[Nytol]

I have used it before, 425mg I think, pre WO, then 10iu slin post WO, it certainly made the slin hit harder, and I went hypo a few times using that combo.

I did not use it for long enough to gauge if the gains were better or not.

[The Animal]

Cheers for the replies dudes.

[Belle1984]

Metformin is given to patients with Type 2 diabetes (usually develops due to poor diet and/or lack of sufficient exercise), particularly used by those who are considered obese and are insulin resistant.

The action of the drug itself is unclear, but it is believed to work by reducing gluconeogenesis (formation of glucose produced from amino acids and also glycerol in liver), decreases glucose absorption from the intestinal tract and increases insulin sensitivity by increasing the need/use of glucose by the body tissue (feeding the muscles).

[Belle1984]

Common side effects: anorexia, nausea, vomiting, diarrhoea, abdo pain, metallic/metal taste in the mouth, decreased vit B12 absorption, redness of the skin (erytherma), itchiness of the skin and hives..

[redman]

Originally Posted by Nytol

I have used it before, 425mg I think, pre WO, then 10iu slin post WO, it certainly made the slin hit harder, and I went hypo a few times using that combo.

I did not use it for long enough to gauge if the gains were better or not.

Cool I was looking for feedback on this.

I think it can increases insulin sensitivity, but I wouldnt like to use with slin.

I was thinking of using it for a couple of weeks pre slin/gh protocol in order to prime insulin sensitivity and make the slin hit harder as it were.

Doing research this comming week.

[Nytol]

It definitely increases sensitivity, but I cant say if it is only while it is in your system, as I only used it in the above manner.

No sides at that dose though, (apart from the hypo).

[redman]

Originally Posted by Nytol

It definitely increases sensitivity, but I cant say if it is only while it is in your system, as I only used it in the above manner.

No sides at that dose though, (apart from the hypo).

Im not worried about going hypo as its easily solved! So I might run both together.

So In laymens terms... the Metformin increases insulin sensitivity allowing more glucose and goodies to be taken up buy the muscle instead of the liver. I guess a glass of orange juice in the morning would help stock up liver glycogen.

Ok Nytol. I usually go with 10iuGH/10iu slin PWO with 60g of WMS "corn flour" 10g of rice olgidextrin and 50g of whey isolate. I never go hypo with this combo I could drop the WMS by around 10g and still be ok but thats just about my cut off point.

Would you suggest taking much more WMS/WHEY in. If so any idea how much.

Thanks mate

[The Animal]

Originally Posted by Belle1984

Metformin is given to patients with Type 2 diabetes (usually develops due to poor diet and/or lack of sufficient exercise), particularly used by those who are considered obese and are insulin resistant.

The action of the drug itself is unclear, but it is believed to work by reducing gluconeogenesis (formation of glucose produced from amino acids and also glycerol in liver), decreases glucose absorption from the intestinal tract and increases insulin sensitivity by increasing the need/use of glucose by the body tissue (feeding the muscles).

Cheers, But I already said I know what is is, and what it's used for.

I want to see peoples opinions on it in bodybuilding.

[The Animal]

Originally Posted by redman

Im not worried about going hypo as its easily solved! So I might run both together.

So In laymens terms... the Metformin increases insulin sensitivity allowing more glucose and goodies to be taken up buy the muscle instead of the liver. I guess a glass of orange juice in the morning would help stock up liver glycogen.

Ok Nytol. I usually go with 10iuGH/10iu slin PWO with 60g of WMS "corn flour" 10g of rice olgidextrin and 50g of whey isolate. I never go hypo with this combo I could drop the WMS by around 10g and still be ok but thats just about my cut off point.

Would you suggest taking much more WMS/WHEY in. If so any idea how much.

Thanks mate

From my reading, thats basically the long and short of it. It is very good at it too.

Markus Ruhl was supposed to be using it at 4500mg PD.

[redman]

Bump for Nytol

Ok Nytol. I usually go with 10iuGH/10iu slin PWO with 60g of WMS "corn flour" 10g of rice olgidextrin and 50g of whey isolate. I never go hypo with this combo I could drop the WMS by around 10g and still be ok but thats just about my cut off point.

Would you suggest taking much more WMS/WHEY in. If so any idea how much.

Thanks mate

[The Animal]

Originally Posted by redman

Bump for Nytol

Ok Nytol. I usually go with 10iuGH/10iu slin PWO with 60g of WMS "corn flour" 10g of rice olgidextrin and 50g of whey isolate. I never go hypo with this combo I could drop the WMS by around 10g and still be ok but thats just about my cut off point.

Would you suggest taking much more WMS/WHEY in. If so any idea how much.

Thanks mate

Just PM him dude.

You'll get a faster answer.

Even start a new thread.

[Nytol]

Originally Posted by redman

Bump for Nytol

Ok Nytol. I usually go with 10iuGH/10iu slin PWO with 60g of WMS "corn flour" 10g of rice olgidextrin and 50g of whey isolate. I never go hypo with this combo I could drop the WMS by around 10g and still be ok but thats just about my cut off point.

Would you suggest taking much more WMS/WHEY in. If so any idea how much.

Thanks mate

Sorry mate, did not see this

I would keep it the same, but just have some extra on hand, I used the combo for about 5-6 weeks, and went hypo 2-3 times, but quite harsh, so it was not always an issue, the other thing was, one occasion it hit me about 4hrs post WO when it should have all been out of my system, that one did take me by surprise TBH, luckily I was at home.

[Joshua]

Has anyone got any experience of how much to alter slin dose/protocol by when using metformin?

Thanks,
J