Quote:
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Originally Posted by Biker Understanding Drug Half-Lives - by William Llewellyn
There are a number of factors that can affect the potency of a particular drug compound. One such factor, and perhaps one of the most important, is the half-life of the agent. In medicine, the term half-life refers to the duration it takes for half of a given drug dosage to break down in the body. It is not half of the total activity time, as this figure always refers to the time it takes to metabolize 50% of what is in still the body. For example, if we inject 100mg a steroid with a half-life of 4 hours, at the four-hour mark we should have only 50mg left as active. After another four hours have passed the drug is still in the body, however another half-life has expired and the total active dosage will be around 25mg. It may take several half-lives before the drug is completely inactive. |
Yes - it may take several half-lives before the drug is completely inactive. But it only takes one active life - which is why I go on this.
It's interesting that you quote Bill Llewellyn on this, as if I remember correctly, he (like me) advocates starting PCT after 2 weeks (i.e. the start of week 3). In fact, I don't think he even recommends running anything more than 20mg ED of nolva in the way of anti-e's during this PCT (his logic is to use HCG).
Post-cycle serves to restore natty test AND LH levels. Sure, you might not be able to get natty test recovery until your levels falls (I DO agree with you on this - I don't think we disagree as much as you think on this), but you CAN attempt to help restore LH levels earlier. In fact it's shown that the body will naturally start to restore LH levels after only 2 weeks for enanthate (the active life).
I also agree with you that active life is dose dependant. However, for the vast majority of "normal range" steroid users, the 2 week enanthate active life is a pretty accurate length.
I really think that Hackskii makes a lot of sense when he says that you need to figure out what's right for you. For me it's definitely 2 weeks - I am happy with that both from a theoretical point of view AND from a practical point of view. I am also happy in the knowledge that if I am wrong, it's not the end of the world - I get my levels checked at the end of PCT and run it longer if necessary.
If only there were FDA guidelines as to when to run PCT after a steroid cycle (yeah right!!).
That said, I am going to be running a cycle a la chefx next - and if I like this way of cycling, I will stick to it - which means I'll only be using fast acting esters - so none of this becomes much of a concern any more.