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The questions still remains, if the problem is not with the pituitary gland, then why does HGH decrease as we age? One theory is that the pituitary gland does not "know" it should be producing more HGH. Our body has a feedback loop that says when the IGF-1 levels decrease, produce more HGH. For some unknown reason it is possible that this loop is broken and the pituitary gland has a harder time getting the signal to produce more HGH as we age.
Another theory is that as we get older our Somatostatin levels increase. Somatostatin is a natural inhibitor to growth hormone. So, as we age the somatostatin levels increase and this leads to a decrease in HGH.
As we speak a lot of very smart people are trying to come up with a definitive answer as to why HGH levels decrease with age, but as of now we just have theories.
How about they did all of the testing of hGH levels on a bunch of fat, sedentary fc-ukers (this would have been since around 1986 when this 'referenence' range was done), who eat a completely ****e diet of simple carbs and modified fats?
Why was this over-looked, gee, that doesn't sell a shed loads of drugs now does it?
Is there any way to maintain high HGH levels as we age?
Yes. Back on our growth hormones definitions page we discussed the recombinant GH that is made by Eli Lilly. A doctor can do a daily injection of this GH and it will lead to an overall increase of growth hormone in the body. It is important to understand that recombinant GH is only available in injection form. The 191 amino acid hormone is too delicate to be made in any oral form
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I am sorry, that is just as evil as Merck pushing the HPV vaccine in women over the age of 20 in the US right now.
There are ways you can naturally increase the secretion of GH.
There is something that doesn't match up when the pituitary makes as much GH in an 80 year old as it does in a 20 year old, it just isn't secreted.
But telling people to modify their lifestyles, sleep well, intense training, eat healthy, and a few amino acid supps doesn't sell any of this majorly expensive drug.
If you are under 40, you don't need GH for any sort of life extension.
There is a new GH that has been developed that will not induce insulin insensitivity quite recently, but how widely available it is yet?
GH exists in about 180 different isoforms in the blood, naturally, and they are only cloning one or two of these isoforms now, they are not going to clone all of the isoforms, nor is it known which ones are bio-active, or if there are specific isoforms for different tissues or functions (yet).
Just do your research, personally, I don't think it is all that as far as a drug therapy goes, yet.