Originally Posted by Z3R0-CooL

when talking about something toxic you are referring to the amount of stress it takes for your liver to remove it from ur bloodstream. Suppression ultimately means HPTA shutdown thus nuts shrinkage and LH/Testicle testosterone production. If your nuts have not shrunk it means that you are not "very" shutdown AFAIK. Also do you have any scientific studies that prove that tren is harsh on the kidneys? I havent been able to find one. Not saying that tren is awesome safe or anything. Im just asking for evidence cause i havent seen any.

Only things i've found:

"The points one may wish to consider during use of Fina is the low sterility of some home-brewed concoctions along with the already relatively painful injections (high alcohol content). This can lead to multiple problems when it is injected daily. Lumps due to plentiful same-site injections, abscesses and infections caused by faulty filtering and so on. Trenbolone is not particularly toxic though. Liver values are barely elevated while using it. Though there is no evidence or explanation to support this, some users reported a certain kidney-toxicity. Blood in urine and all that. While this was no doubt the result of a fake (Finaject used to be an often faked steroid shortly after its discontinuation) but I figured I'd mention it. Other than that mild androgenic effects such as acne and an increase in hair loss are noted as well."

"Short-term side effects include insomnia, high blood pressure, increased aggression, night sweats, and libido. However, since women will suffer virilization effects even at small doses, this drug should not be taken by a female. Urban wisdom/myth in bodybuilding culture, states that the use of the drug over extended periods of time can lead to kidney damage. The kidney toxicity has not yet been proven, and scientific evidence supporting the idea is suspiciously absent from the bodybuilding community that perpetuates this idea. The origin of this myth most likely has to do with the rust colored oxidized metabolites of trenbolone which are excreted in urine and often mistaken for blood. After Schänzer (Clin Chem 1996; 42(7): 1001-1020, Metabolism of anabolic androgenic steroids) trenbolone and 17epi-trenbolone are both excreted (in urine) as conjugates that can be hydrolyzed with beta-glucuronidase. This implies that trenbolone leaves the body as beta-glucuronides or sulfates, that means mostly non metabolized."