Originally Posted by andr0lic

With regard to prostaglandin inhibition, I have noticed that when i supplement in excess of 6 or 7 grams of fish oil a day, I start to lose some of my size and fullness, especially post-workout, when Prostaglandin formation is so important. Over the years using and experimenting with many different doses of fish oil, I've found for me, that too much fish-oil is counter-intuitive to acheiving the desired anabolic state. My eyes don't lie, and the outcome is the same repeatedly whenever i dose too high on my Omega-3's. The correlation could be drawn with 100% pure cherry juice or ibuprofen. yes they will lower inflammation to a degree but if too much is administered, the decrease in prostaglandin activity then becomes deletrious. In contrast, no matter how much flax oil i have ever used, i've never encountered the reduced fullness and muscle-wasting effects as seen with high dose fish oil. let that be a testament to the inefficacy of flax oil as an omega-3 supplement.

When you are taking flax, you are also taking in LA (omega 6 parent EFA), which then promotes series 1, and potentially, series 2 prostaglandin formation. This will probably underline the difference you have mentioned, as opposed to flax being innefectual.

(the series 2 formation is down regulated by series 1 & 3 prostaglandins, however, it will provide for more substrate - i.e. AA, which itself is seen as useful for growth - though I'm not certain that recent AA supplements are heading in the right direction)

I hadn't heard about cherry juice before - maybe that's why I didn't burn in Turkey a few years ago when I was drinking tonnes of the stuff...

I would bet that a lot of you out there who reduced your fish oil intake back to 6 or so grams a day would allow yourselves to reap the maximum benefits of its anti-inflammatory and hormonal optimizing effects.


-Andy Androlic