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Old 24-03-2006, 02:58 PM   #7 (permalink)
Tatyana
My name is EARL
 
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Join Date: Jan 2006
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Insulin resistance is usually a disorder of the elderly or obese. It basically means there is too much body for the amount of insulin produced. A drop in weight of 10-15% usually corrects this.

As for the cell surface receptor 'damage', I had thought that it was hydrogenated fats that 'block up' the glucose receptors.

There are 5 categories of glucose receptors, some are tissue specific, called GLUT 1 through 5.

GLUT 4 is stored in the cytoplasm of the cell and is transported to the cell surface under the influence of insulin and increases the uptake of glucose by 6-10 x.

GLUT 1 and 3 are always present on the cell surface, (GLUT 1 is on RBCs or red blood cells).

I do have loads more info on GLUT receptors, I love my cell and molecular biology.

Last edited by Tatyana; 24-03-2006 at 03:04 PM.
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